81377  München christian.haass(at)dzne.de +49 89 4400-46549 Areas of investigation/research focus Prof. Haass started to work on Alzheimer's disease (AD) rein 1990 at a time, when very little welches known about the cellular mechanisms involved.  Based on the pathology, which shows invariably the accumulation and deposition of Amyloid ß-peptide (Aß), he focused his work on the generation and metabolism of Aß.  Christian Haass hypothesized against the widely accepted general opinion in this field that Aß may Beryllium produced from its precursor hinein a physiologically weit verbreitet pathway and not necessarily in a pathological process.  Indeed he found by using very simple tissue culture systems that Aß is produced and liberated under physiological conditions.  This pivotal finding welches a major breakthrough for the entire field, since it allowed elucidating the molecular principles behind Aß generation as well as the identification of the enzymes (the so-called secretases) involved in generation and liberation of the peptide and finally the development of selective inhibitors to therapeutically lower Aß production rein patients.

We also use third-party cookies that help us analyze and understand how you use this website. These cookies will Beryllium stored in your browser only with your consent. You also have the option to opt-out of these cookies. But opting out of some of these cookies may affect your browsing experience.

Chris­t­ian Haass is a German Biochemist and known for his work on the cell biology of neurode­gen­er­a­tive diseases.

If you are lacking driving practice or simply haven't driven a car rein a long time and have got out of the habit, we can help you get back into it with a few refresher lessons.

This website uses cookies to improve your experience while you navigate through the website. Out of these, the cookies that are categorized as necessary are stored on your browser as they are essential for the working of Beginners all purpose symbolic instruction code functionalities of the website.

Together with an inter­dizipli­nary Mannschaft he uncov­ered the molec­u­lar mecha­nisms of Alzheimer's disease and identi­fied target molecules for thera­peu­tic treatment.

Yes, a trial lesson is always possible and of course free of Lot; if you decide to register with us, this trial lesson will Beryllium credited to you as "attended". I would like to register at Momo's Driving School. When can I come by?

Zudem haben registrierte User die Möglichkeit eine überprüfe hier Route mit dem PC auf falk.de nach entwerfen, nach fassen ebenso anschließend mit dem Smartphone Freund und feind wohlig abzurufen.

You can do following driving classes with us. Click on each class to get more information. Class B

Performance cookies are used to understand and analyze the key performance indexes of the website which helps hinein delivering a better user experience for the visitors. Analytics Analytics

  Very recently he also investigated the role of microglia and inflammation rein neurodegenerative disorders.  This work Leuchtdiode to the spectacular finding that microglial phagocytosis may be impaired late during neurodegeneration and opened up a completely unexpected road towards new therapeutic developments for patients already developing disease symptoms.  This work resulted rein the identification of TREM2 as a CSF marker for microglial activity.  Hinein a unique cohort of subjects with autosomal dominant AD, CSF sTREM2 was abnormally increased 5 years before the expected onset of symptoms. This will not only greatly facilitate research on inflammatory disease overarching mechanisms, but may also provide a very valuable therapeutic marker.

We will give you driving lessons designed to suit your own particular needs not only during the week but also on Saturdays. Hinein this way you will get your driving licence as quickly as possible.

Leichte zweirädrige Kraftfahrzeuge mit einer durch die Bauart bestimmten Höchstgeschwindigkeit von nicht etliche als 45 stundenkilometer, einer Nenndauerleistung/Nutzleistung von nicht mehr wie 4 kW und einem Verbrennungsmotor mit einem Hubraum von nicht etliche denn 50 cm³ oder einer anderen Antriebsform.

We work on the molecular and cellular mechanisms of neurodegeneration with a strong focus on Alzheimer’s disease and related disorders. We are searching for therapeutic targets within the amyloid cascade. Secretases, amyloid metabolism and microglial function are within the focus of our research.